Assay Detail
Binding
CHEMBL1021285
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase activity after 20 mins
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Studies on depigmenting activities of dihydroxyl benzamide derivatives containing adamantane moiety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.96 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL450195 | RUCINOL | — | 1 | 6.82 |
| CHEMBL474953 | — | — | 1 | 6.05 |
| CHEMBL537 | HYDROQUINONE | 4.0 | 1 | 5.01 |
| CHEMBL516395 | — | — | 1 | - |
| CHEMBL474954 | — | — | 1 | - |
| CHEMBL514970 | — | — | 1 | - |
| CHEMBL474952 | — | — | 1 | - |
| CHEMBL474951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL450195 | RUCINOL | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL474953 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL537 | HYDROQUINONE | IC50 | = | 9810.0 | nM | 5.01 |
| CHEMBL516395 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL474954 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL514970 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL474952 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL474951 | — | IC50 | > | 200000.0 | nM | - |