Assay Detail
Binding
CHEMBL1021768
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Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometrically
6
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.23 | 6.00 |
| Ki | 3 | 7.27 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87474 | — | — | 1 | 8.28 |
| CHEMBL469655 | — | — | 1 | 7.22 |
| CHEMBL502230 | — | — | 2 | 6.31 |
| CHEMBL458368 | — | — | 1 | 4.46 |
| CHEMBL443158 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87474 | — | Ki | = | 5.3 | nM | 8.28 |
| CHEMBL469655 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL502230 | — | Ki | = | 490.0 | nM | 6.31 |
| CHEMBL502230 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL458368 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL443158 | — | IC50 | = | 150000.0 | nM | - |