Assay Detail
Binding
CHEMBL1021775
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Inhibition of yeast maltase alpha-glucosidase assessed as p-nitrophenol release by spectrophotometrically
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.30 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80254 | — | — | 1 | 6.08 |
| CHEMBL312653 | — | — | 1 | 5.70 |
| CHEMBL247666 | — | — | 1 | 4.11 |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
| CHEMBL471888 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80254 | — | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL312653 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL247666 | — | IC50 | = | 78000.0 | nM | 4.11 |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 110000.0 | nM | - |
| CHEMBL471888 | — | IC50 | = | 260000.0 | nM | - |