Assay Detail
Binding
CHEMBL1022064
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Inhibition of RSK2 C-terminal kinase domain expressed in Escherichia coli preincubated for 30 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.82 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL515414 | — | — | 1 | 4.82 |
| CHEMBL473965 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL515414 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL473965 | — | IC50 | = | 1200000.0 | nM | - |