Assay Detail
Binding
CHEMBL1022889
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of radioligand from progesterone receptor by fluorescence polarization assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.32 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL474189 | — | — | 1 | 7.51 |
| CHEMBL473801 | — | — | 1 | 7.47 |
| CHEMBL514630 | — | — | 1 | 7.46 |
| CHEMBL514646 | — | — | 1 | 6.83 |
| CHEMBL474770 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL474189 | — | Ki | = | 31.0 | nM | 7.51 |
| CHEMBL473801 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL514630 | — | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL514646 | — | Ki | = | 147.0 | nM | 6.83 |
| CHEMBL474770 | — | Ki | > | 10000.0 | nM | - |