Assay Detail
Binding
CHEMBL1023030
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant PDE4B3 assessed as inhibition of cAMP hydrolysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3',5'-cyclic-AMP phosphodiesterase 4B (CHEMBL275) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Dual inhibitors of phosphodiesterase-4 and serotonin reuptake.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.53 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505431 | — | — | 1 | 6.70 |
| CHEMBL313041 | — | — | 1 | 6.60 |
| CHEMBL451500 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505431 | — | Ki | = | 199.0 | nM | 6.70 |
| CHEMBL313041 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL451500 | — | Ki | = | 500.0 | nM | 6.30 |