Assay Detail
Functional
CHEMBL1023650
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Cytotoxicity against CD30 expressing and CD70 deficient human L540cy cells after 96 hrs by resazurin conversion assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | L540cy |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.10 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11417 | STREPTONIGRIN | 2.0 | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11417 | STREPTONIGRIN | IC50 | = | 0.8 | nM | 9.10 |