Assay Detail
Functional
CHEMBL1024366
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Varicella zoster virus in HFF assessed as inhibition of virus-induced cytopathic effect
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.54 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL554910 | — | — | 1 | 5.54 |
| CHEMBL265948 | FILOCICLOVIR | 2.0 | 1 | - |
| CHEMBL372938 | — | — | 1 | - |
| CHEMBL572812 | — | — | 1 | - |
| CHEMBL550615 | — | — | 1 | - |
| CHEMBL559499 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL554910 | — | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL265948 | FILOCICLOVIR | EC50 | > | 380000.0 | nM | - |
| CHEMBL372938 | — | EC50 | > | 301000.0 | nM | - |
| CHEMBL572812 | — | EC50 | = | 191000.0 | nM | - |
| CHEMBL550615 | — | EC50 | > | 300000.0 | nM | - |
| CHEMBL559499 | — | EC50 | > | 300000.0 | nM | - |