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Target Snapshot

CHEMBL613132 Target Snapshot

Human alphaherpesvirus 3 · ORGANISM · Human alphaherpesvirus 3

1,734Compounds
489Assays
10Approved Drugs
3,408.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Human alphaherpesvirus 3 as ChEMBL target CHEMBL613132. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Human alphaherpesvirus 3
ORGANISM · Human alphaherpesvirus 3
As of 2026-09-14
ChEMBL target ID
CHEMBL613132
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Human alphaherpesvirus 3 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHuman alphaherpesvirus 3
UniProt AccessionN/A

Human alphaherpesvirus 3

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Human alphaherpesvirus 3.

Review nameHuman alphaherpesvirus 3
OrganismHuman alphaherpesvirus 3
Clinical Profile

Clinical Phase Distribution

10
Approved
5
Phase III
4
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC50649.0
EC502,759.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL342983 10.74 IC50 0.018 Preclinical
CHEMBL484 10.46 IC50 0.035 Clinical
CHEMBL57548 10.27 IC50 0.05357 Preclinical
CHEMBL356695 10.08 IC50 0.084 Preclinical
CHEMBL147862 10.0 EC50 0.1 Preclinical
CHEMBL344738 10.0 EC50 0.1 Preclinical
CHEMBL146699 9.96 IC50 0.11 Preclinical
CHEMBL56641 9.91 IC50 0.1241 Preclinical
CHEMBL57384 9.91 IC50 0.1241 Preclinical
CHEMBL299704 9.86 IC50 0.1374 Preclinical
Distribution

pChEMBL Value Distribution

270
5.0
185
5.5
114
6.0
98
6.5
91
7.0
73
7.5
65
8.0
25
8.5
23
9.0
25
9.5
pChEMBL
Approved Drugs

Approved Drugs

CIDOFOVIR ANHYDROUS
CHEMBL152
Approved 1996
GEMCITABINE
CHEMBL888
Approved 1996
CIDOFOVIR
CHEMBL5314375
Approved 1996
PENCICLOVIR
CHEMBL1540
Approved 1996
GANCICLOVIR
CHEMBL182
Approved 1989
ACYCLOVIR
CHEMBL184
Approved 1982
Assay Landscape

Assay Landscape

489
Total Assays
825
Tested Compounds
1
Assay Types
Functional — 489 assays, 825 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 459 646 5.9
cell-based format 24 162 5.3
assay format 6 17 5.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine