Assay Detail
Binding
CHEMBL1025647
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Displacement of [3H]DPCPX from adenosine A1 receptor in Syrian hamster DDT1 MF2 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mesocricetus auratus |
| Cell Type | DDT1 MF2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of bivalent beta2-adrenergic and adenosine A1 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.16 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | — | 1 | 8.05 |
| CHEMBL524037 | — | — | 1 | 6.36 |
| CHEMBL462274 | — | — | 1 | 5.99 |
| CHEMBL493489 | — | — | 1 | 5.72 |
| CHEMBL462273 | — | — | 1 | 5.72 |
| CHEMBL517259 | — | — | 1 | 5.70 |
| CHEMBL460361 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL524037 | — | Ki | = | 436.0 | nM | 6.36 |
| CHEMBL462274 | — | Ki | = | 1014.0 | nM | 5.99 |
| CHEMBL493489 | — | Ki | = | 1907.0 | nM | 5.72 |
| CHEMBL462273 | — | Ki | = | 1914.0 | nM | 5.72 |
| CHEMBL517259 | — | Ki | = | 1979.0 | nM | 5.70 |
| CHEMBL460361 | — | Ki | = | 2749.0 | nM | 5.56 |