Assay Detail

CHEMBL1027005

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Functional

Effect on luciferase activity in human Hep3B cells exposed to hypoxic condition for 16 hrs

ChEMBL ↗

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Target

Hep 3B2 (CHEMBL4296437) ↗

Open DB target context

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Primary target Hep 3B2

CHEMBL4296437

Anchored from Assay target.

Protein identity Hep 3B2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Hep 3B2
Confidence	1 — Organism
Curated By	Autocuration

Target

Hep 3B2 (CHEMBL4296437) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species.

Dat NT, Jin X, Lee K, Hong YS, Kim YH, Lee JJ.
J Nat Prod (2009) 72 : 39 -43
PubMed 19072214 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	9.00	9.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL205924	MORACIN O	—	1	9.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL205924	MORACIN O	EC50	=	1.0	nM	9.00