Assay Detail
Binding
CHEMBL1027053
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellum
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Cerebellum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Design and synthesis of novel delta opioid receptor agonists and their pharmacologies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.95 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559518 | — | — | 1 | 9.44 |
| CHEMBL564538 | — | — | 1 | 8.36 |
| CHEMBL552308 | — | — | 1 | 7.99 |
| CHEMBL567175 | NALTRINDOLE | — | 1 | 7.85 |
| CHEMBL327745 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559518 | — | Ki | = | 0.36 | nM | 9.44 |
| CHEMBL564538 | — | Ki | = | 4.41 | nM | 8.36 |
| CHEMBL552308 | — | Ki | = | 10.2 | nM | 7.99 |
| CHEMBL567175 | NALTRINDOLE | Ki | = | 14.01 | nM | 7.85 |
| CHEMBL327745 | — | Ki | = | 732.45 | nM | 6.13 |