Assay Detail

CHEMBL1027133

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Functional

Cytotoxicity against human HCT116 cells

ChEMBL ↗

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Target

HCT-116 (CHEMBL394) ↗

Open DB target context

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Primary target HCT-116

CHEMBL394

Anchored from Assay target.

Protein identity HCT-116

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HCT-116
Confidence	1 — Organism
Curated By	Autocuration

Target

HCT-116 (CHEMBL394) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.

Sashidhara KV, White KN, Crews P.
J Nat Prod (2009) 72 : 588 -603
PubMed 19209899 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	5.26	5.26

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL521352	18-EPI-LATRUNCULOL A	—	1	5.26
CHEMBL490508	MYCOTHIAZOLE	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL521352	18-EPI-LATRUNCULOL A	IC50	=	5500.0	nM	5.26
CHEMBL490508	MYCOTHIAZOLE	IC50	=	0.0015	ug.mL-1	-