HCT-116 · CELL-LINE · Homo sapiens
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HCT-116
Review this target as HCT-116.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HCT-116 as ChEMBL target CHEMBL394. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | HCT-116 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as HCT-116.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL187738 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL846 | 11.0 | IC50 | 0.01 | Approved |
| CHEMBL4205723 | 10.8 | IC50 | 0.016 | Preclinical |
| CHEMBL492573 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL441018 | 10.57 | IC50 | 0.027 | Preclinical |
| CHEMBL200899 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL1808822 | 10.35 | IC50 | 0.045 | Preclinical |
| CHEMBL1808826 | 10.35 | IC50 | 0.045 | Preclinical |
| CHEMBL492975 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL1808829 | 10.28 | IC50 | 0.053 | Preclinical |