Assay Detail
ADMET
CHEMBL1027262
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Drug level in rat brain at 30 mg/kg, ip by LC-MS/MS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.77 | 6.77 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| DOSE | DOSE | 30.0 | mg.kg-1 | — |
| ROUTE | ROUTE | - | — | Intraperitoneal |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL492438 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL492438 | — | IC50 | = | 170.0 | nM | 6.77 |