Assay Detail
Functional
CHEMBL1027646
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of endotoxin-induced tissue factor expression after 18 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Monocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.75 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291426 | HINOKIFLAVONE | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291426 | HINOKIFLAVONE | IC50 | = | 18.0 | nM | 7.75 |