Assay Detail
Binding
CHEMBL1029935
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Inhibition of Huntingtin protein aggregation by yeast based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Potent inhibitors of Huntingtin protein aggregation in a cell-based assay.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449571 | — | — | 1 | 4.30 |
| CHEMBL494325 | — | — | 1 | 4.30 |
| CHEMBL494326 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449571 | — | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL494325 | — | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL494326 | — | EC50 | = | 50000.0 | nM | 4.30 |