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Assay Detail

CHEMBL1031960

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human liver FBPase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Fructose-1,6-bisphosphatase 1 (CHEMBL3975)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase.
Heng S, Gryncel KR, Kantrowitz ER.
Bioorg Med Chem (2009) 17 : 3916 -3922
PubMed 19419876 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.80 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL495498 MB-05032 2.0 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL495498 MB-05032 EC50 = 16.0 nM 7.80