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Assay Detail

CHEMBL1034005

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Functional
Antiviral activity against Human herpesvirus 8
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human gammaherpesvirus 8
Confidence 1 — Organism
Curated By Autocuration

Target

Human gammaherpesvirus 8 (CHEMBL612780)
Type ORGANISM
Organism Human gammaherpesvirus 8

Publication

Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Prado-Prado FJ, Martinez de la Vega O, Uriarte E, Ubeira FM, Chou KC, González-Díaz H.
Bioorg Med Chem (2009) 17 : 569 -575
PubMed 19112024 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.24 4.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL157102 1 4.24
CHEMBL152335 1 -
CHEMBL151794 1 -
CHEMBL347817 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL157102 IC50 = 57000.0 nM 4.24
CHEMBL152335 IC50 = 165000.0 nM -
CHEMBL151794 IC50 = 197000.0 nM -
CHEMBL347817 IC50 = 190000.0 nM -