Assay Detail
Functional
CHEMBL1034009
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Antiviral activity against influenza H2N2 virus
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | H2N2 subtype |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.78 | 9.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | -1.0 | 1 | 9.77 |
| CHEMBL221722 | FAVIPIRAVIR | 4.0 | 1 | 7.32 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 6.12 |
| CHEMBL1229 | OSELTAMIVIR | 4.0 | 1 | 5.84 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | IC50 | = | 0.17 | nM | 9.77 |
| CHEMBL221722 | FAVIPIRAVIR | IC50 | = | 48.0 | nM | 7.32 |
| CHEMBL222813 | ZANAMIVIR | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL1229 | OSELTAMIVIR | IC50 | = | 1450.0 | nM | 5.84 |
| CHEMBL1643 | RIBAVIRIN | IC50 | = | 13800.0 | nM | 4.86 |