Assay Detail
Binding
CHEMBL1034387
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of yeast alpha-glucosidase assessed as D-glucose release after 30 mins by Glucose B-test
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Oligo-1,6-glucosidase IMA1 (CHEMBL5848) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.07 | 4.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL488157 | — | — | 1 | 4.07 |
| CHEMBL488156 | — | — | 1 | - |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
| CHEMBL407337 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL488157 | — | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL488156 | — | IC50 | = | 220000.0 | nM | - |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 330000.0 | nM | - |
| CHEMBL407337 | — | IC50 | = | 250000.0 | nM | - |