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Assay Detail

CHEMBL1035053

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat intestinal lactase assessed as p-nitrophenol release after 30 mins by spectrophotometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lactase/phlorizin hydrolase (CHEMBL3389)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica.
Yamashita T, Yasuda K, Kizu H, Kameda Y, Watson AA, Nash RJ, Fleet GW, Asano N.
J Nat Prod (2002) 65 : 1875 -1881
PubMed 12502331 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.75 4.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL524631 HYACINTHACINE B3 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL524631 HYACINTHACINE B3 IC50 = 18000.0 nM 4.75