Assay Detail
Functional
CHEMBL1036714
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Induction of ABCA1 mRNA expression in mouse J774 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | J774 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Biarylether amide quinolines as liver X receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.84 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL450409 | — | — | 1 | 7.47 |
| CHEMBL214719 | — | — | 1 | 7.39 |
| CHEMBL460198 | — | — | 1 | 7.16 |
| CHEMBL480298 | — | — | 1 | 6.38 |
| CHEMBL518033 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL450409 | — | EC50 | = | 34.0 | nM | 7.47 |
| CHEMBL214719 | — | EC50 | = | 41.0 | nM | 7.39 |
| CHEMBL460198 | — | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL480298 | — | EC50 | = | 420.0 | nM | 6.38 |
| CHEMBL518033 | — | EC50 | = | 1600.0 | nM | 5.80 |