Assay Detail
Functional
CHEMBL1036720
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at PPARgamma in transiently transfected cells by Gal4 transactivation assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Biarylether amide quinolines as liver X receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 3 | - | - |
| EC50 | 2 | 5.81 | 6.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL214719 | — | — | 1 | 6.20 |
| CHEMBL480298 | — | — | 1 | 5.42 |
| CHEMBL450409 | — | — | 1 | - |
| CHEMBL518033 | — | — | 1 | - |
| CHEMBL460198 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL214719 | — | EC50 | = | 630.0 | nM | 6.20 |
| CHEMBL480298 | — | EC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL450409 | — | Activity | - | — | - | |
| CHEMBL518033 | — | Activity | - | — | - | |
| CHEMBL460198 | — | Activity | - | — | - |