Assay Detail
Binding
CHEMBL1037271
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human ENT1 in SK-PC1 cells by flow cytometry
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | SK-PC1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Equilibrative nucleoside transporter 1 (CHEMBL1997) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Towards to hENT1-nucleoside transporter selective imaging agents. Synthesis and in vitro evaluation of the radiolabeled SAENTA analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.40 | 9.40 |
| Bmax | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL569224 | — | — | 2 | 9.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL569224 | — | Kd | = | 0.4 | nM | 9.40 |
| CHEMBL569224 | — | Bmax | = | 2.6 | MFU | - |