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Assay Detail

CHEMBL1037510

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as ABTS free radical scavenging activity by radical cation discoloration assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles.
Cressier D, Prouillac C, Hernandez P, Amourette C, Diserbo M, Lion C, Rima G.
Bioorg Med Chem (2009) 17 : 5275 -5284
PubMed 19502068 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 16 4.34 5.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL565519 1 5.08
CHEMBL567156 1 4.67
CHEMBL568739 1 4.64
CHEMBL196 ASCORBIC ACID 4.0 1 4.33
CHEMBL568463 1 4.29
CHEMBL568738 1 4.12
CHEMBL579393 1 4.11
CHEMBL111654 2-MERCAPTOBENZOTHIAZOLE 1 4.10
CHEMBL568708 1 4.05
CHEMBL571946 1 4.04
CHEMBL567806 1 -
CHEMBL567216 1 -
CHEMBL565952 1 -
CHEMBL565780 1 -
CHEMBL579039 1 -
CHEMBL568740 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL565519 IC50 = 8320.0 nM 5.08
CHEMBL567156 IC50 = 21260.0 nM 4.67
CHEMBL568739 IC50 = 23080.0 nM 4.64
CHEMBL196 ASCORBIC ACID IC50 = 46460.0 nM 4.33
CHEMBL568463 IC50 = 51850.0 nM 4.29
CHEMBL568738 IC50 = 76660.0 nM 4.12
CHEMBL579393 IC50 = 76870.0 nM 4.11
CHEMBL111654 2-MERCAPTOBENZOTHIAZOLE IC50 = 79840.0 nM 4.10
CHEMBL568708 IC50 = 88350.0 nM 4.05
CHEMBL571946 IC50 = 90330.0 nM 4.04
CHEMBL567806 IC50 = 1520000.0 nM -
CHEMBL567216 IC50 = 4040000.0 nM -
CHEMBL565952 IC50 = 390000.0 nM -
CHEMBL565780 IC50 - -
CHEMBL579039 IC50 - -
CHEMBL568740 IC50 - -