Assay Detail
Functional
CHEMBL1039519
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Antiproliferative activity against human LS 174T cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LS174T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Sulforaphane induces cell-cycle arrest and apoptosis in cultured human lung adenocarcinoma LTEP-A2 cells and retards growth of LTEP-A2 xenografts in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.59 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | — | 1 | 5.16 |
| CHEMBL48802 | SULFORAPHANE | 3.0 | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL48802 | SULFORAPHANE | IC50 | = | 95000.0 | nM | 4.02 |