Assay Detail
Binding
CHEMBL1039601
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]yohimbine from alpha2 adrenergic receptor in rat brain cortex by liquid scintillation counting
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.90 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL583422 | — | — | 1 | 6.64 |
| CHEMBL566533 | — | — | 1 | 5.87 |
| CHEMBL565707 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL583422 | — | Ki | = | 231.0 | nM | 6.64 |
| CHEMBL566533 | — | Ki | = | 1350.0 | nM | 5.87 |
| CHEMBL565707 | — | Ki | = | 6480.0 | nM | 5.19 |