Assay Detail
Binding
CHEMBL1040388
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Binding affinity to 5-HT2C receptor
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Identification of novel serotonin 2C receptor ligands by sequential virtual screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 8.69 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL575849 | — | — | 1 | 9.05 |
| CHEMBL494947 | — | — | 1 | 9.00 |
| CHEMBL574985 | — | — | 1 | 9.00 |
| CHEMBL573131 | — | — | 1 | 8.62 |
| CHEMBL303516 | — | — | 1 | 8.48 |
| CHEMBL203013 | — | — | 1 | 8.40 |
| CHEMBL573354 | — | — | 1 | 8.28 |
| CHEMBL378946 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL575849 | — | Ki | = | 0.89 | nM | 9.05 |
| CHEMBL494947 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL574985 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL573131 | — | Ki | = | 2.4 | nM | 8.62 |
| CHEMBL303516 | — | Ki | = | 3.3 | nM | 8.48 |
| CHEMBL203013 | — | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL573354 | — | Ki | = | 5.2 | nM | 8.28 |
| CHEMBL378946 | — | Ki | > | 20000.0 | nM | - |