Compound Detail
CHEMBL575849
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Basic Information
| ChEMBL ID | CHEMBL575849 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QLOOWOVVZLBYHU-SECBINFHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
243.3
MW (Da)
2.69
ALogP
4
HBA
1
HBD
57.0
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C CHEMBL225 | Ki | 9.05 | 9.05 | 0.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | Ki | = | 0.89 | nM | 9.05 | Binding affinity to 5-HT2C receptor | 19464901 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19464901 | 10.1016/j.bmc.2009.05.003 | 5-hydroxytryptamine receptor 2C | 1 |
Data from ChEMBL 36 via Core Engine