Assay Detail
Functional
CHEMBL1041197
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Antiviral activity against Dengue virus
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Dengue virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The medicinal chemistry of dengue fever.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.15 | 6.00 |
| EC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL311226 | CASTANOSPERMINE | -1.0 | 1 | 6.00 |
| CHEMBL304087 | MERIMEPODIB | 2.0 | 1 | 5.10 |
| CHEMBL582943 | — | — | 1 | 4.34 |
| CHEMBL575429 | — | — | 1 | - |
| CHEMBL574855 | — | — | 1 | - |
| CHEMBL574190 | — | — | 1 | - |
| CHEMBL575724 | — | — | 1 | - |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL311226 | CASTANOSPERMINE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL304087 | MERIMEPODIB | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL582943 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL575429 | — | IC50 | = | 2000000.0 | nM | - |
| CHEMBL574855 | — | IC50 | = | 2000000.0 | nM | - |
| CHEMBL574190 | — | IC50 | = | 2000000.0 | nM | - |
| CHEMBL575724 | — | IC50 | = | 294000.0 | nM | - |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 49.0 | ug.mL-1 | - |