Assay Detail
Functional
CHEMBL1042222
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Antioxidant activity assessed as superoxide free radical scavenging activity after 60 mins by xanthine oxidase method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antityrosinase and antioxidant effects of ent-kaurane diterpenes from leaves of Broussonetia papyrifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.20 | 4.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL577801 | BROUSSONETONE C | — | 1 | 4.36 |
| CHEMBL574535 | BROUSSONETONE B | — | 1 | 4.27 |
| CHEMBL28 | APIGENIN | — | 1 | 4.09 |
| CHEMBL487417 | VITEXIN | — | 1 | 4.07 |
| CHEMBL574312 | BROUSSONETONE A | — | 1 | - |
| CHEMBL4296740 | BUTYLATED HYDROXYANISOLE | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL577801 | BROUSSONETONE C | IC50 | = | 43890.0 | nM | 4.36 |
| CHEMBL574535 | BROUSSONETONE B | IC50 | = | 53900.0 | nM | 4.27 |
| CHEMBL28 | APIGENIN | IC50 | = | 81270.0 | nM | 4.09 |
| CHEMBL487417 | VITEXIN | IC50 | = | 84950.0 | nM | 4.07 |
| CHEMBL574312 | BROUSSONETONE A | IC50 | = | 107700.0 | nM | - |
| CHEMBL4296740 | BUTYLATED HYDROXYANISOLE | IC50 | - | — | - |