Assay Detail
Functional
CHEMBL1042907
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiinflammatory activity in C57/Bl6 mouse CD4+ T cells assessed as inhibition of anti-CD3/anti-CD28 antibody-stimulated INFgamma production after 18 hrs by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | T-cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nucleoside-5'-monophosphates as prodrugs of adenosine A2A receptor agonists activated by ecto-5'-nucleotidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.27 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL568023 | — | — | 1 | 7.30 |
| CHEMBL577046 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL568023 | — | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL577046 | — | EC50 | = | 5700.0 | nM | 5.24 |