Assay Detail
Binding
CHEMBL1045251
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human somatic ACE in presence of 1:50 diluted SHR rat plasma
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.80 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL570953 | — | — | 1 | 8.10 |
| CHEMBL567628 | — | — | 1 | 6.47 |
| CHEMBL577754 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL570953 | — | Ki | = | 8.0 | nM | 8.10 |
| CHEMBL567628 | — | Ki | = | 340.0 | nM | 6.47 |
| CHEMBL577754 | — | Ki | = | 1520.0 | nM | 5.82 |