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Assay Detail

CHEMBL1045996

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type 1321-N1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

P2Y purinoceptor 2 (CHEMBL4398)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose.
Ko H, Das A, Carter RL, Fricks IP, Zhou Y, Ivanov AA, Melman A, Joshi BV, Kovác P, Hajduch J, Kirk KL, Harden TK, Jacobson KA.
Bioorg Med Chem (2009) 17 : 5298 -5311
PubMed 19502066 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL375951 URIDINE DIPHOSPHATE GLUCOSE 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL375951 URIDINE DIPHOSPHATE GLUCOSE EC50 = 10000.0 nM 5.00