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Assay Detail

CHEMBL1047740

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human immunodeficiency virus 1 3B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

The search for potent, small molecule NNRTIs: A review.
Prajapati DG, Ramajayam R, Yadav MR, Giridhar R.
Bioorg Med Chem (2009) 17 : 5744 -5762
PubMed 19632850 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL54893 UC 781 1.0 1 7.82
CHEMBL190729 1 7.82
CHEMBL595002 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL54893 UC 781 EC50 = 15.0 nM 7.82
CHEMBL190729 EC50 = 15.0 nM 7.82
CHEMBL595002 EC50 = 15.0 nM 7.82