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Assay Detail

CHEMBL1047792

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as inhibition of Fe3+ ion-induced 2-deoxyribose oxidation after 24 hrs by TBA method
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Antioxidant efficacy of iridoid and phenylethanoid glycosides from the medicinal plant Teucrium chamaedris in cell-free systems.
Pacifico S, D'Abrosca B, Pascarella MT, Letizia M, Uzzo P, Piscopo V, Fiorentino A.
Bioorg Med Chem (2009) 17 : 6173 -6179
PubMed 19674906 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 12 4.55 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL595773 1 4.89
CHEMBL596187 1 4.88
CHEMBL153 TROLOX 1 4.75
CHEMBL444478 ACETOSIDE 2.0 1 4.58
CHEMBL593634 1 4.58
CHEMBL608705 1 4.50
CHEMBL595333 1 4.47
CHEMBL595544 1 4.46
CHEMBL595516 1 4.43
CHEMBL595383 1 4.43
CHEMBL595293 1 4.29
CHEMBL605532 1 4.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL595773 IC50 = 12900.0 nM 4.89
CHEMBL596187 IC50 = 13200.0 nM 4.88
CHEMBL153 TROLOX IC50 = 18000.0 nM 4.75
CHEMBL444478 ACETOSIDE IC50 = 26400.0 nM 4.58
CHEMBL593634 IC50 = 26500.0 nM 4.58
CHEMBL608705 IC50 = 32000.0 nM 4.50
CHEMBL595333 IC50 = 33500.0 nM 4.47
CHEMBL595544 IC50 = 34600.0 nM 4.46
CHEMBL595516 IC50 = 36800.0 nM 4.43
CHEMBL595383 IC50 = 37300.0 nM 4.43
CHEMBL595293 IC50 = 51000.0 nM 4.29
CHEMBL605532 IC50 = 52200.0 nM 4.28