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Assay Detail

CHEMBL1048017

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Binding
Inhibition of rat recombinant FAAH expressed in Escherichia coli
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Fatty-acid amide hydrolase 1 (CHEMBL3229)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase.
Mileni M, Garfunkle J, Ezzili C, Kimball FS, Cravatt BF, Stevens RC, Boger DL.
J Med Chem (2010) 53 : 230 -240
PubMed 19924997 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.33 8.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL177577 1 8.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL177577 Ki = 4.7 nM 8.33