Assay Detail
Binding
CHEMBL1049707
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Inhibition of factor 10a
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 4.24 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL566340 | — | — | 1 | 4.40 |
| CHEMBL569280 | — | — | 1 | 4.08 |
| CHEMBL568067 | — | — | 1 | - |
| CHEMBL568525 | — | — | 1 | - |
| CHEMBL569918 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL566340 | — | Ki | = | 40000.0 | nM | 4.40 |
| CHEMBL569280 | — | Ki | = | 83000.0 | nM | 4.08 |
| CHEMBL568067 | — | Ki | = | 123000.0 | nM | - |
| CHEMBL568525 | — | Ki | - | — | - | |
| CHEMBL569918 | — | Ki | - | — | - |