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Assay Detail

CHEMBL1050429

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 5HT2B receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2B (CHEMBL1833)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.
Peng Y, Zhang Q, Arora S, Keenan SM, Kortagere S, Wannemacher KM, Howells RD, Welsh WJ.
Bioorg Med Chem (2009) 17 : 6442 -6450
PubMed 19646882 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.11 5.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL595449 1 5.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL595449 IC50 = 7745.0 nM 5.11