Assay Detail
Binding
CHEMBL1050562
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Inhibition of TX synthase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.38 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL483900 | — | — | 1 | 6.10 |
| CHEMBL412099 | — | — | 1 | 5.52 |
| CHEMBL565406 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL483900 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL412099 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL565406 | — | IC50 | = | 30000.0 | nM | 4.52 |