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Assay Detail

CHEMBL1050880

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane after 90 mins by scintillation counting
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Cerebellum
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Cannabinoid receptor 1 (CHEMBL3571)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide.
Cano C, Páez JA, Goya P, Serrano A, Pavón J, Rodríguez de Fonseca F, Suardíaz M, Martín MI.
Eur J Med Chem (2009) 44 : 4889 -4895
PubMed 19762126 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL374746 1 5.37
CHEMBL219156 1 -
CHEMBL437157 1 -
CHEMBL218643 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL374746 Ki = 4229.0 nM 5.37
CHEMBL219156 Ki > 10000.0 nM -
CHEMBL437157 Ki > 100000.0 nM -
CHEMBL218643 Ki > 10000.0 nM -