Assay Detail
ADMET
CHEMBL1052285
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Cytotoxicity against rat RBL2H3 cells after 12 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | RBL-2H3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.23 | 4.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL555195 | — | — | 1 | 4.42 |
| CHEMBL25948 | SHOGAOL | — | 1 | 4.04 |
| CHEMBL402978 | GINGEROL | -1.0 | 1 | - |
| CHEMBL549472 | — | — | 1 | - |
| CHEMBL479650 | HEXAHYDROCURCUMIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL555195 | — | IC50 | = | 38500.0 | nM | 4.42 |
| CHEMBL25948 | SHOGAOL | IC50 | = | 90400.0 | nM | 4.04 |
| CHEMBL402978 | GINGEROL | IC50 | = | 185100.0 | nM | - |
| CHEMBL549472 | — | IC50 | = | 111700.0 | nM | - |
| CHEMBL479650 | HEXAHYDROCURCUMIN | IC50 | = | 152300.0 | nM | - |