Assay Detail
Functional
CHEMBL1054972
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity against mouse CRTh2 receptor expressed in K562 cells by [35S]GTPgamma binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | K562 |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
7-Azaindole-3-acetic acid derivatives: potent and selective CRTh2 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.78 | 6.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL563949 | — | — | 1 | 6.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL563949 | — | IC50 | = | 167.0 | nM | 6.78 |