Assay Detail
Functional
CHEMBL1055732
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human RD1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RD1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.77 | 6.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL564417 | — | — | 1 | 6.84 |
| CHEMBL401930 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL564417 | — | IC50 | = | 146.0 | nM | 6.84 |
| CHEMBL401930 | — | IC50 | = | 202.0 | nM | 6.70 |