Assay Detail

CHEMBL1056201

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Inhibition of luciferase expression in human Hep3B cells after 16 hrs under hypoxic condition

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Hep 3B2 (CHEMBL4296437) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Hep 3B2 (CHEMBL4296437) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Hep 3B2

CHEMBL4296437

Anchored from Assay target.

Protein identity Hep 3B2

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Hep 3B2
Confidence	1 — Organism
Curated By	Autocuration

Target

Hep 3B2 (CHEMBL4296437) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species.

Dat NT, Jin X, Lee K, Hong YS, Kim YH, Lee JJ.
J Nat Prod (2009) 72 : 39 -43
PubMed 19072214 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.75	8.75

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL205924	MORACIN O	—	1	8.75

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL205924	MORACIN O	IC50	=	1.79	nM	8.75