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Assay Detail

CHEMBL1057901

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity in human HL60 cells assessed as inhibition of relative oxygen species generation by DCFH-DA method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.
Li J, Ding Y, Li XC, Ferreira D, Khan S, Smillie T, Khan IA.
J Nat Prod (2009) 72 : 983 -987
PubMed 19555121 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL196 ASCORBIC ACID 4.0 1 8.00
CHEMBL117 CHRYSIN 1 -
CHEMBL183513 OROXYLIN A 1 -
CHEMBL16171 WOGONIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL196 ASCORBIC ACID IC50 = 10.0 nM 8.00
CHEMBL117 CHRYSIN IC50 - -
CHEMBL183513 OROXYLIN A IC50 - -
CHEMBL16171 WOGONIN IC50 - -