Assay Detail

CHEMBL1059618

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Functional

Cytotoxicity against human HL60 cells after 72 hrs

ChEMBL ↗

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Target

HL-60 (CHEMBL383) ↗

Open DB target context

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Primary target HL-60

CHEMBL383

Anchored from Assay target.

Protein identity HL-60

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HL-60
Confidence	1 — Organism
Curated By	Autocuration

Target

HL-60 (CHEMBL383) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Synthesis and cytotoxicities of icogenin analogues with disaccharide residues.

Wang H, Su F, Zhou L, Chen X, Lei P.
Bioorg Med Chem Lett (2009) 19 : 2796 -2800
PubMed 19362474 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.58	5.58

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL550365	ICOGENIN(BETA)	—	1	5.58

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL550365	ICOGENIN(BETA)	IC50	=	2600.0	nM	5.58