Assay Detail
Functional
CHEMBL1059624
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Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Bel-7402 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and cytotoxicities of icogenin analogues with disaccharide residues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.12 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507001 | DIOSCIN | — | 1 | 6.64 |
| CHEMBL888 | GEMCITABINE | 4.0 | 1 | 6.08 |
| CHEMBL550365 | ICOGENIN(BETA) | — | 1 | 6.07 |
| CHEMBL552748 | — | — | 1 | 6.05 |
| CHEMBL540242 | — | — | 1 | 6.04 |
| CHEMBL552749 | — | — | 1 | 6.03 |
| CHEMBL500045 | GRACILLIN | — | 1 | 5.96 |
| CHEMBL554848 | — | — | 1 | - |
| CHEMBL395646 | POLYPHILLIN C | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507001 | DIOSCIN | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL888 | GEMCITABINE | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL550365 | ICOGENIN(BETA) | IC50 | = | 860.0 | nM | 6.07 |
| CHEMBL552748 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL540242 | — | IC50 | = | 920.0 | nM | 6.04 |
| CHEMBL552749 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL500045 | GRACILLIN | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL554848 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL395646 | POLYPHILLIN C | IC50 | > | 10000.0 | nM | - |