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Assay Detail

CHEMBL1061258

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to amyloid beta (1 to 42) peptide
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Fluoro-pegylated chalcones as positron emission tomography probes for in vivo imaging of beta-amyloid plaques in Alzheimer's disease.
Ono M, Watanabe R, Kawashima H, Cheng Y, Kimura H, Watanabe H, Haratake M, Saji H, Nakayama M.
J Med Chem (2009) 52 : 6394 -6401
PubMed 19757822 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.17 8.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL566752 FLORBETABEN F18 4.0 1 8.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL566752 FLORBETABEN F18 Ki = 6.7 nM 8.17